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Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation

MutLα endonuclease can be activated on covalently continuous DNA that contains a MutSα- or MutSβ-recognizable lesion and a helix perturbation that supports proliferating cell nuclear antigen (PCNA) loading by replication factor C, providing a potential mechanism for triggering mismatch repair on non...

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Detalhes bibliográficos
Main Authors: Pluciennik, Anna, Burdett, Vickers, Baitinger, Celia, Iyer, Ravi R., Shi, Kevin, Modrich, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725108/
https://ncbi.nlm.nih.gov/pubmed/23840062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311325110
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