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Structure of the endonuclease domain of MutL: unlicensed to cut

DNA mismatch repair corrects errors that have escaped polymerase proofreading, increasing replication fidelity 100- to 1000-fold in organisms ranging from bacteria to humans. The MutL protein plays a central role in mismatch repair by coordinating multiple protein-protein interactions that signal st...

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Detalhes bibliográficos
Main Authors: Pillon, Monica C., Lorenowicz, Jessica J., Uckelmann, Michael, Klocko, Andrew D., Mitchell, Ryan R., Chung, Yu Seon, Modrich, Paul, Walker, Graham C., Simmons, Lyle A., Friedhoff, Peter, Guarné, Alba
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933357/
https://ncbi.nlm.nih.gov/pubmed/20603082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.06.027
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