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The endonuclease domain of MutL interacts with the β sliding clamp
Mismatch repair corrects errors that have escaped polymerase proofreading enhancing replication fidelity by at least two orders of magnitude. The β and PCNA sliding clamps increase the polymerase processivity during DNA replication and are important at several stages of mismatch repair. Both MutS an...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028594/ https://ncbi.nlm.nih.gov/pubmed/21050827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.10.003 |
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