Loading...
HER3 signaling is regulated through a multitude of redundant mechanisms in HER2-driven tumor cells
HER2-amplified tumors are characterized by constitutive signaling via the HER2-HER3 co-receptor complex. While phosphorylation activity is driven entirely by the HER2 kinase, signal volume generated by the complex is under control of HER3 and a large capacity to increase its signaling output account...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3722874/ https://ncbi.nlm.nih.gov/pubmed/22853430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120724 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|