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The HER family and cancer: emerging molecular mechanisms and therapeutic targets
The human epidermal growth factor receptor (HER) family of transmembrane tyrosine kinases regulate diverse cellular functions in response to extracellular ligands. The deregulation of HER signaling through gene amplification or mutation is seen in many human tumors and an abundance of experimental e...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035105/ https://ncbi.nlm.nih.gov/pubmed/17981505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2007.10.002 |
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