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The HER family and cancer: emerging molecular mechanisms and therapeutic targets
The human epidermal growth factor receptor (HER) family of transmembrane tyrosine kinases regulate diverse cellular functions in response to extracellular ligands. The deregulation of HER signaling through gene amplification or mutation is seen in many human tumors and an abundance of experimental e...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035105/ https://ncbi.nlm.nih.gov/pubmed/17981505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2007.10.002 |
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