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Promoter directionality is controlled by U1 snRNP and polyadenylation signals
Transcription of the mammalian genome is pervasive but productive transcription outside protein-coding genes is limited by unknown mechanisms(1). In particular, although RNA polymerase II (RNAPII) initiates divergently from most active gene promoters, productive elongation occurs primarily in the se...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3720719/ https://ncbi.nlm.nih.gov/pubmed/23792564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12349 |
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