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Promoter directionality is controlled by U1 snRNP and polyadenylation signals

Transcription of the mammalian genome is pervasive but productive transcription outside protein-coding genes is limited by unknown mechanisms(1). In particular, although RNA polymerase II (RNAPII) initiates divergently from most active gene promoters, productive elongation occurs primarily in the se...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Almada, Albert E., Wu, Xuebing, Kriz, Andrea J., Burge, Christopher B., Sharp, Phillip A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720719/
https://ncbi.nlm.nih.gov/pubmed/23792564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12349
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