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Recovery of Endothelial Cell Prostacyclin Production after Inhibition by Low Doses of Aspirin

Endothelial cells synthesize prostacyclin (PGI(2)), an unstable prostaglandin that inhibits platelet aggregation and serotonin release. Because cyclooxygenase, which is necessary for synthesis of PGI(2), is inactivated by aspirin, we examined the effect of aspirin on PGI(2) production by cultured hu...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Jaffe, Eric A., Weksler, Babette B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1979
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/372242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109332
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