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Nitroglycerin Stimulates Synthesis of Prostacyclin by Cultured Human Endothelial Cells

Nitroglycerin (NTG), the agent most commonly used to treat acute angina pectoris, is a vasodilator whose mechanism of action remains unknown. We hypothesized that NTG might induce endothelial cells to synthesize prostacyclin (PGI(2)), a known vasodilator and inhibitor of platelet aggregation. Theref...

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Autori principali: Levin, Richard I., Jaffe, Eric A., Weksler, Babette B., Tack-Goldman, Karen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1981
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC370627/
https://ncbi.nlm.nih.gov/pubmed/6782121
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