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Recovery of Endothelial Cell Prostacyclin Production after Inhibition by Low Doses of Aspirin

Endothelial cells synthesize prostacyclin (PGI(2)), an unstable prostaglandin that inhibits platelet aggregation and serotonin release. Because cyclooxygenase, which is necessary for synthesis of PGI(2), is inactivated by aspirin, we examined the effect of aspirin on PGI(2) production by cultured hu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Jaffe, Eric A., Weksler, Babette B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/372242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109332
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