Recovery of Endothelial Cell Prostacyclin Production after Inhibition by Low Doses of Aspirin

Endothelial cells synthesize prostacyclin (PGI(2)), an unstable prostaglandin that inhibits platelet aggregation and serotonin release. Because cyclooxygenase, which is necessary for synthesis of PGI(2), is inactivated by aspirin, we examined the effect of aspirin on PGI(2) production by cultured hu...

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Pubblicato in:	J Clin Invest
Autori principali:	Jaffe, Eric A., Weksler, Babette B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1979
Soggetti:	Rapid Publications
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/372242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109332
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