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Synthesis of Prostacyclin from Platelet-derived Endoperoxides by Cultured Human Endothelial Cells

We have previously shown that aspirin-treated endothelial cells synthesize prostacyclin (PGI(2)) from the purified prostaglandin endoperoxide PGH(2) (1978. J. Biol. Chem.253: 7138). To ascertain whether aspirin-treated endothelial cells produce PGI(2) from endoperoxides released by stimulated platel...

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Publicat a:J Clin Invest
Autors principals: Marcus, Aaron J., Weksler, Babette B., Jaffe, Eric A., Broekman, M. Johan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1980
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371534/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6776148/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109967
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