Effect of fatty acid modification on prostacyclin production by cultured human endothelial cells.

We have investigated whether changes in cellular fatty acid saturation can influence prostacyclin (PGI2) production by cultured human umbilical vein endothelial cells. As compared to control cells, those enriched with linoleic acid released 60--75% less PGI2 in response to thrombin or the calcium io...

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Autori principali: Spector, A A, Hoak, J C, Fry, G L, Denning, G M, Stoll, L L, Smith, J B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC371430/
https://ncbi.nlm.nih.gov/pubmed/6767738
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