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Effect of fatty acid modification on prostacyclin production by cultured human endothelial cells.

We have investigated whether changes in cellular fatty acid saturation can influence prostacyclin (PGI2) production by cultured human umbilical vein endothelial cells. As compared to control cells, those enriched with linoleic acid released 60--75% less PGI2 in response to thrombin or the calcium io...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Spector, A A, Hoak, J C, Fry, G L, Denning, G M, Stoll, L L, Smith, J B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1980
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371430/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6767738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109752
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