Effect of fatty acid modification on prostacyclin production by cultured human endothelial cells.

We have investigated whether changes in cellular fatty acid saturation can influence prostacyclin (PGI2) production by cultured human umbilical vein endothelial cells. As compared to control cells, those enriched with linoleic acid released 60--75% less PGI2 in response to thrombin or the calcium io...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Spector, A A, Hoak, J C, Fry, G L, Denning, G M, Stoll, L L, Smith, J B
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1980
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6767738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109752
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