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Nitroglycerin Stimulates Synthesis of Prostacyclin by Cultured Human Endothelial Cells

Nitroglycerin (NTG), the agent most commonly used to treat acute angina pectoris, is a vasodilator whose mechanism of action remains unknown. We hypothesized that NTG might induce endothelial cells to synthesize prostacyclin (PGI(2)), a known vasodilator and inhibitor of platelet aggregation. Theref...

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Udgivet i:J Clin Invest
Principais autores: Levin, Richard I., Jaffe, Eric A., Weksler, Babette B., Tack-Goldman, Karen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1981
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370627/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6782121/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110093
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