Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.
Cultured endothelial cells derived from human umbilical veins or bovine aorta produce a potent inhibitor of platelet aggregation. The inhibitor is synthesized from sodium arachidonate or or prostaglandin endoperoxides by a microsomal enzyme system. Tranylcypromine, a specific antagonist of prostacyc...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1977
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/333448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.9.3922 |
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