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Distinction between the Cfr Methyltransferase Conferring Antibiotic Resistance and the Housekeeping RlmN Methyltransferase

The cfr gene encodes the Cfr methyltransferase that primarily methylates C-8 in A2503 of 23S rRNA in the peptidyl transferase region of bacterial ribosomes. The methylation provides resistance to six classes of antibiotics of clinical and veterinary importance. The rlmN gene encodes the RlmN methylt...

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Main Authors: Atkinson, Gemma C., Hansen, Lykke H., Tenson, Tanel, Rasmussen, Anette, Kirpekar, Finn, Vester, Birte
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719738/
https://ncbi.nlm.nih.gov/pubmed/23752511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00448-13
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