Distinction between the Cfr Methyltransferase Conferring Antibiotic Resistance and the Housekeeping RlmN Methyltransferase

The cfr gene encodes the Cfr methyltransferase that primarily methylates C-8 in A2503 of 23S rRNA in the peptidyl transferase region of bacterial ribosomes. The methylation provides resistance to six classes of antibiotics of clinical and veterinary importance. The rlmN gene encodes the RlmN methylt...

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Библиографические подробности
Главные авторы: Atkinson, Gemma C., Hansen, Lykke H., Tenson, Tanel, Rasmussen, Anette, Kirpekar, Finn, Vester, Birte
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Mechanisms of Resistance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719738/
https://ncbi.nlm.nih.gov/pubmed/23752511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00448-13
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