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A cfr-Like Gene from Clostridium difficile Confers Multiple Antibiotic Resistance by the Same Mechanism as the cfr Gene

The Cfr RNA methyltransferase causes multiple resistances to peptidyl transferase inhibitors by methylation of A2503 23S rRNA. Many cfr-like gene sequences in the databases code for unknown functions. This study confirms that a Cfr-like protein from a Peptoclostridium difficile (formerly Clostridium...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hansen, Lykke H., Vester, Birte
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538495/
https://ncbi.nlm.nih.gov/pubmed/26149991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01274-15
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