cfr(B), cfr(C), and a New cfr-Like Gene, cfr(E), in Clostridium difficile Strains Recovered across Latin America

Cfr is a radical S-adenosyl-l-methionine (SAM) enzyme that confers cross-resistance to antibiotics targeting the 23S rRNA through hypermethylation of nucleotide A2503. Three cfr-like genes implicated in antibiotic resistance have been described, two of which, cfr(B) and cfr(C), have been sporadicall...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stojković, Vanja, Ulate, María Fernanda, Hidalgo-Villeda, Fanny, Aguilar, Emmanuel, Monge-Cascante, Camilo, Pizarro-Guajardo, Marjorie, Tsai, Kaitlyn, Tzoc, Edgardo, Camorlinga, Margarita, Paredes-Sabja, Daniel, Quesada-Gómez, Carlos, Fujimori, Danica Galonić, Rodríguez, César
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187602/
https://ncbi.nlm.nih.gov/pubmed/31685464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01074-19
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