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Combined Effect of the Cfr Methyltransferase and Ribosomal Protein L3 Mutations on Resistance to Ribosome-Targeting Antibiotics

Several groups of antibiotics inhibit bacterial growth by binding to bacterial ribosomes. Mutations in ribosomal protein L3 have been associated with resistance to linezolid and tiamulin, which both bind at the peptidyl transferase center in the ribosome. Resistance to these and other antibiotics al...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Pakula, Kevin K., Hansen, Lykke H., Vester, Birte
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571294/
https://ncbi.nlm.nih.gov/pubmed/28630201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00862-17
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