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Combined Effect of the Cfr Methyltransferase and Ribosomal Protein L3 Mutations on Resistance to Ribosome-Targeting Antibiotics

Several groups of antibiotics inhibit bacterial growth by binding to bacterial ribosomes. Mutations in ribosomal protein L3 have been associated with resistance to linezolid and tiamulin, which both bind at the peptidyl transferase center in the ribosome. Resistance to these and other antibiotics al...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Pakula, Kevin K., Hansen, Lykke H., Vester, Birte
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571294/
https://ncbi.nlm.nih.gov/pubmed/28630201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00862-17
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