Distinction between the Cfr Methyltransferase Conferring Antibiotic Resistance and the Housekeeping RlmN Methyltransferase

The cfr gene encodes the Cfr methyltransferase that primarily methylates C-8 in A2503 of 23S rRNA in the peptidyl transferase region of bacterial ribosomes. The methylation provides resistance to six classes of antibiotics of clinical and veterinary importance. The rlmN gene encodes the RlmN methylt...

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Detalhes bibliográficos
Main Authors: Atkinson, Gemma C., Hansen, Lykke H., Tenson, Tanel, Rasmussen, Anette, Kirpekar, Finn, Vester, Birte
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719738/
https://ncbi.nlm.nih.gov/pubmed/23752511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00448-13
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