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Granulocyte-Macrophage Colony-Stimulating Factor-Armed Oncolytic Measles Virus Is an Effective Therapeutic Cancer Vaccine

Oncolytic measles viruses (MV) derived from the live attenuated vaccine strain have been engineered for increased antitumor activity, and are currently under investigation in clinical phase 1 trials. Approaches with other viral vectors have shown that insertion of immunomodulatory transgenes enhance...

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Detaylı Bibliyografya
Asıl Yazarlar: Grossardt, Christian, Engeland, Christine E., Bossow, Sascha, Halama, Niels, Zaoui, Karim, Leber, Mathias F., Springfeld, Christoph, Jaeger, Dirk, von Kalle, Christof, Ungerechts, Guy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719441/
https://ncbi.nlm.nih.gov/pubmed/23642239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.205
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