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Granulocyte-Macrophage Colony-Stimulating Factor-Armed Oncolytic Measles Virus Is an Effective Therapeutic Cancer Vaccine

Oncolytic measles viruses (MV) derived from the live attenuated vaccine strain have been engineered for increased antitumor activity, and are currently under investigation in clinical phase 1 trials. Approaches with other viral vectors have shown that insertion of immunomodulatory transgenes enhance...

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Detalhes bibliográficos
Main Authors: Grossardt, Christian, Engeland, Christine E., Bossow, Sascha, Halama, Niels, Zaoui, Karim, Leber, Mathias F., Springfeld, Christoph, Jaeger, Dirk, von Kalle, Christof, Ungerechts, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719441/
https://ncbi.nlm.nih.gov/pubmed/23642239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.205
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