Granulocyte-Macrophage Colony-Stimulating Factor-Armed Oncolytic Measles Virus Is an Effective Therapeutic Cancer Vaccine

Oncolytic measles viruses (MV) derived from the live attenuated vaccine strain have been engineered for increased antitumor activity, and are currently under investigation in clinical phase 1 trials. Approaches with other viral vectors have shown that insertion of immunomodulatory transgenes enhance...

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Main Authors: Grossardt, Christian, Engeland, Christine E., Bossow, Sascha, Halama, Niels, Zaoui, Karim, Leber, Mathias F., Springfeld, Christoph, Jaeger, Dirk, von Kalle, Christof, Ungerechts, Guy
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2013
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719441/
https://ncbi.nlm.nih.gov/pubmed/23642239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.205
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