miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221&222

Non-small cell lung cancer (NSCLC) accounts for approximately 80% of all lung cancers. While some advances in lung cancer therapy have been made, patient survival is still quite poor. Two microRNAs, miR-221 and miR-222, up-regulated by the MET proto-oncogene, have been already described to enhance c...

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Bibliografiske detaljer
Main Authors: Acunzo, Mario, Visone, Rosa, Romano, Giulia, Veronese, Angelo, Lovat, Francesca, Palmieri, Dario, Bottoni, Arianna, Garofalo, Michela, Gasparini, Pierluigi, Condorelli, Gerolama, Chiariello, Mario, Croce, Carlo Maria
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719419/
https://ncbi.nlm.nih.gov/pubmed/21706050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.260
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