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miR-221/222 Target the DNA Methyltransferase MGMT in Glioma Cells
Glioblastoma multiforme (GBM) is one of the most deadly types of cancer. To date, the best clinical approach for treatment is based on administration of temozolomide (TMZ) in combination with radiotherapy. Much evidence suggests that the intracellular level of the alkylating enzyme O(6)-methylguanin...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798259/ https://ncbi.nlm.nih.gov/pubmed/24147153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074466 |
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