miR-221/222 Target the DNA Methyltransferase MGMT in Glioma Cells

Glioblastoma multiforme (GBM) is one of the most deadly types of cancer. To date, the best clinical approach for treatment is based on administration of temozolomide (TMZ) in combination with radiotherapy. Much evidence suggests that the intracellular level of the alkylating enzyme O(6)-methylguanin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Quintavalle, Cristina, Mangani, Davide, Roscigno, Giuseppina, Romano, Giulia, Diaz-Lagares, Angel, Iaboni, Margherita, Donnarumma, Elvira, Fiore, Danilo, De Marinis, Pasqualino, Soini, Ylermi, Esteller, Manel, Condorelli, Gerolama
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798259/
https://ncbi.nlm.nih.gov/pubmed/24147153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074466
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