miR-221/222 Target the DNA Methyltransferase MGMT in Glioma Cells

Glioblastoma multiforme (GBM) is one of the most deadly types of cancer. To date, the best clinical approach for treatment is based on administration of temozolomide (TMZ) in combination with radiotherapy. Much evidence suggests that the intracellular level of the alkylating enzyme O(6)-methylguanin...

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Dades bibliogràfiques
Autors principals: Quintavalle, Cristina, Mangani, Davide, Roscigno, Giuseppina, Romano, Giulia, Diaz-Lagares, Angel, Iaboni, Margherita, Donnarumma, Elvira, Fiore, Danilo, De Marinis, Pasqualino, Soini, Ylermi, Esteller, Manel, Condorelli, Gerolama
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798259/
https://ncbi.nlm.nih.gov/pubmed/24147153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074466
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