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Solution structure of the Grb2 SH2 domain complexed with a high-affinity inhibitor

The solution structure of the growth factor receptor-bound protein 2 (Grb2) SH2 domain complexed with a high-affinity inhibitor containing a non-phosphorus phosphate mimetic within a macrocyclic platform was determined by nuclear magnetic resonance (NMR) spectroscopy. Unambiguous assignments of the...

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Autors principals: Ogura, Kenji, Shiga, Takanori, Yokochi, Masashi, Yuzawa, Satoru, Burke, Terrence R., Inagaki, Fuyuhiko
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719385/
https://ncbi.nlm.nih.gov/pubmed/18830565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-008-9272-0
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