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Solution structure of the Grb2 SH2 domain complexed with a high-affinity inhibitor
The solution structure of the growth factor receptor-bound protein 2 (Grb2) SH2 domain complexed with a high-affinity inhibitor containing a non-phosphorus phosphate mimetic within a macrocyclic platform was determined by nuclear magnetic resonance (NMR) spectroscopy. Unambiguous assignments of the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719385/ https://ncbi.nlm.nih.gov/pubmed/18830565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-008-9272-0 |
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