Novel recognition mode between Vav and Grb2 SH3 domains

Vav is a guanine nucleotide exchange factor for the Rho/Rac family that is expressed exclusively in hematopoietic cells. Growth factor receptor-bound protein 2 (Grb2) has been proposed to play important roles in the membrane localization and activation of Vav through dimerization of its C-terminal S...

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Autores principales: Nishida, Motohiko, Nagata, Koji, Hachimori, Yukiko, Horiuchi, Masataka, Ogura, Kenji, Mandiyan, Valsan, Schlessinger, Joseph, Inagaki, Fuyuhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC150196/
https://ncbi.nlm.nih.gov/pubmed/11406576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.2995
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