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Novel recognition mode between Vav and Grb2 SH3 domains
Vav is a guanine nucleotide exchange factor for the Rho/Rac family that is expressed exclusively in hematopoietic cells. Growth factor receptor-bound protein 2 (Grb2) has been proposed to play important roles in the membrane localization and activation of Vav through dimerization of its C-terminal S...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150196/ https://ncbi.nlm.nih.gov/pubmed/11406576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.2995 |
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