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Tissue-Nonspecific Alkaline Phosphatase Acts Redundantly with PAP and NT5E to Generate Adenosine in the Dorsal Spinal Cord
Prostatic acid phosphatase (PAP) and ecto-5′-nucleotidase (NT5E) hydrolyze extracellular AMP to adenosine in dorsal root ganglia (DRG) neurons and in the dorsal spinal cord. Previously, we found that adenosine production was reduced, but not eliminated, in Pap(−/−)/Nt5e(−/−) double knock-out (dKO) m...
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Autori principali: | , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Society for Neuroscience
2013
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718384/ https://ncbi.nlm.nih.gov/pubmed/23825434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0133-13.2013 |
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