Tissue-Nonspecific Alkaline Phosphatase Acts Redundantly with PAP and NT5E to Generate Adenosine in the Dorsal Spinal Cord

Prostatic acid phosphatase (PAP) and ecto-5′-nucleotidase (NT5E) hydrolyze extracellular AMP to adenosine in dorsal root ganglia (DRG) neurons and in the dorsal spinal cord. Previously, we found that adenosine production was reduced, but not eliminated, in Pap(−/−)/Nt5e(−/−) double knock-out (dKO) m...

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Egile Nagusiak: Street, Sarah E., Kramer, Nicholas J., Walsh, Paul L., Taylor-Blake, Bonnie, Yadav, Manisha C., King, Ian F., Vihko, Pirkko, Wightman, R. Mark, Millán, José Luis, Zylka, Mark J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2013
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Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718384/
https://ncbi.nlm.nih.gov/pubmed/23825434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0133-13.2013
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