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Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning
Metabotropic glutamate receptor 5 (mGluR5) plays important roles in modulating neural activity and plasticity and has been associated with several neuropathological disorders. Previous work has shown that genetic ablation or pharmacological inhibition of mGluR5 disrupts fear extinction and spatial r...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718201/ https://ncbi.nlm.nih.gov/pubmed/23869026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.031666.113 |
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