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Transgene- and locus-dependent imprinting reveals allele-specific chromosome conformations

When positioned into the integrin α-6 gene, an Hoxd9lacZ reporter transgene displayed parental imprinting in mouse embryos. While the expression from the paternal allele was comparable with patterns seen for the same transgene when present at the neighboring HoxD locus, almost no signal was scored a...

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Autores principales: Lonfat, Nicolas, Montavon, Thomas, Jebb, David, Tschopp, Patrick, Nguyen Huynh, Thi Hanh, Zakany, Jozsef, Duboule, Denis
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718164/
https://ncbi.nlm.nih.gov/pubmed/23818637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310704110
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