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Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus
Copy number variations are genomic structural variants that are frequently associated with human diseases. Among these copy number variations, duplications of DNA segments are often assumed to lead to dosage effects by increasing the copy number of either genes or their regulatory elements. We produ...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528568/ https://ncbi.nlm.nih.gov/pubmed/23134724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217659109 |
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