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Chromatin topology and the timing of enhancer function at the HoxD locus

The HoxD gene cluster is critical for proper limb formation in tetrapods. In the emerging limb buds, different subgroups of Hoxd genes respond first to a proximal regulatory signal, then to a distal signal that organizes digits. These two regulations are exclusive from one another and emanate from t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Rodríguez-Carballo, Eddie, Lopez-Delisle, Lucille, Willemin, Andréa, Beccari, Leonardo, Gitto, Sandra, Mascrez, Bénédicte, Duboule, Denis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733857/
https://ncbi.nlm.nih.gov/pubmed/33229569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2015083117
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