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Chromatin topology and the timing of enhancer function at the HoxD locus

The HoxD gene cluster is critical for proper limb formation in tetrapods. In the emerging limb buds, different subgroups of Hoxd genes respond first to a proximal regulatory signal, then to a distal signal that organizes digits. These two regulations are exclusive from one another and emanate from t...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Rodríguez-Carballo, Eddie, Lopez-Delisle, Lucille, Willemin, Andréa, Beccari, Leonardo, Gitto, Sandra, Mascrez, Bénédicte, Duboule, Denis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733857/
https://ncbi.nlm.nih.gov/pubmed/33229569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2015083117
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