Large scale genomic reorganization of topological domains at the HoxD locus

BACKGROUND: The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster. In particular, the activation of the most posterior HoxD genes in developing digits is controlled by r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Fabre, Pierre J., Leleu, Marion, Mormann, Benjamin H., Lopez-Delisle, Lucille, Noordermeer, Daan, Beccari, Leonardo, Duboule, Denis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547506/
https://ncbi.nlm.nih.gov/pubmed/28784160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1278-z
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