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Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain

Embryogenesis requires the precise activation and repression of many transcriptional regulators. The Polycomb group proteins and the associated H3K27me3 histone mark are essential to maintain the inactive state of many of these genes. Mammalian Hox genes are targets of Polycomb proteins and form loc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Vieux-Rochas, Maxence, Fabre, Pierre J., Leleu, Marion, Duboule, Denis, Noordermeer, Daan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403207/
https://ncbi.nlm.nih.gov/pubmed/25825760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504783112
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