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Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain
Embryogenesis requires the precise activation and repression of many transcriptional regulators. The Polycomb group proteins and the associated H3K27me3 histone mark are essential to maintain the inactive state of many of these genes. Mammalian Hox genes are targets of Polycomb proteins and form loc...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403207/ https://ncbi.nlm.nih.gov/pubmed/25825760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504783112 |
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