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Large scale genomic reorganization of topological domains at the HoxD locus
BACKGROUND: The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster. In particular, the activation of the most posterior HoxD genes in developing digits is controlled by r...
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| Publié dans: | Genome Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547506/ https://ncbi.nlm.nih.gov/pubmed/28784160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1278-z |
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