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A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus

Polycomb group (PcG) proteins are essential for the repression of key factors during early development. In Drosophila, the polycomb repressive complexes (PRC) associate with defined polycomb response DNA elements (PREs). In mammals, however, the mechanisms underlying polycomb recruitment at targeted...

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Détails bibliographiques
Auteurs principaux: Schorderet, Patrick, Lonfat, Nicolas, Darbellay, Fabrice, Tschopp, Patrick, Gitto, Sandra, Soshnikova, Natalia, Duboule, Denis
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820793/
https://ncbi.nlm.nih.gov/pubmed/24244202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003951
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