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Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr

During embryonic development, Hox genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal, growth retardation. Recently, this phenotype was obtained after deletion of Haglr, the Hoxd antisense g...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zakany, Jozsef, Darbellay, Fabrice, Mascrez, Bénédicte, Necsulea, Anamaria, Duboule, Denis
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676926/
https://ncbi.nlm.nih.gov/pubmed/29042517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712511114
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