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Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape

Vertebrate Hox genes encode transcription factors operating during the development of multiple organs and structures. However, the evolutionary mechanism underlying this remarkable pleiotropy remains to be fully understood. Here, we show that Hoxd8 and Hoxd9, two genes of the HoxD complex, are trans...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Schep, Ruben, Necsulea, Anamaria, Rodríguez-Carballo, Eddie, Guerreiro, Isabel, Andrey, Guillaume, Nguyen Huynh, Thi Hanh, Marcet, Virginie, Zákány, Jozsef, Duboule, Denis, Beccari, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137715/
https://ncbi.nlm.nih.gov/pubmed/27856734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617141113
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