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Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo

OBJECTIVE: We had previously reported a mouse line carrying the Atypical female courtship (HoxD(Afc)) allele, where an ectopic accumulation of Hoxd10 transcripts was observed in a sparse population of cells in the adult isocortex, as a result of a partial deletion of the HoxD gene cluster. Female mi...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Zakany, Jozsef, Duboule, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870235/
https://ncbi.nlm.nih.gov/pubmed/29580290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3307-8
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