Transgene- and locus-dependent imprinting reveals allele-specific chromosome conformations

When positioned into the integrin α-6 gene, an Hoxd9lacZ reporter transgene displayed parental imprinting in mouse embryos. While the expression from the paternal allele was comparable with patterns seen for the same transgene when present at the neighboring HoxD locus, almost no signal was scored a...

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Main Authors: Lonfat, Nicolas, Montavon, Thomas, Jebb, David, Tschopp, Patrick, Nguyen Huynh, Thi Hanh, Zakany, Jozsef, Duboule, Denis
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718164/
https://ncbi.nlm.nih.gov/pubmed/23818637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310704110
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