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Nucleotide Release Sequences in the Protein Kinase SRPK1 Accelerate Substrate Phosphorylation()
Protein kinases are essential signaling enzymes that transfer phosphates from bound ATP to select amino acids in protein targets. For most kinases, the phosphoryl transfer step is highly efficient while the rate-limiting step for substrate processing involves slow release of the product ADP. It is g...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718016/ https://ncbi.nlm.nih.gov/pubmed/22839969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300876h |
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