Partitioning RS Domain Phosphorylation in an SR Protein through the CLK and SRPK Protein Kinases

SR proteins are essential splicing factors whose biological function is regulated through phosphorylation of their C-terminal RS domains. Prior studies have shown that cytoplasmic–nuclear translocalization of the SR protein SRSF1 is regulated by multisite phosphorylation of a long Arg-Ser repeat in...

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Autors principals: Aubol, Brandon E., Plocinik, Ryan M., Hagopian, Jonathan C., Ma, Chen-Ting, McGlone, Maria L., Bandyopadhyay, Reeti, Fu, Xiang-Dong, Adams, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860265/
https://ncbi.nlm.nih.gov/pubmed/23707382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.05.013
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